Three-dimensional structure of Theiler virus.
نویسندگان
چکیده
منابع مشابه
Three-dimensional structure of Theiler murine encephalomyelitis virus (BeAn strain).
Depending on the strain, Theiler murine encephalomyelitis virus (TMEV) may cause acute encephalitis or chronic demyelinating disease, which is associated with viral persistence in mice. Persistent central nervous system infection and demyelination by the less-virulent TMEV has provided a useful animal model for the human demyelinating disease multiple sclerosis. The less-virulent BeAn strain of...
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• natural hosts: wild mice [1], laboratory mice, [2] [3] [4], water , bank and meadow voles (family Microtinae) [5] [6] • positive serological reactions in laboratory rats [7] [8]; virus might be related to TMEV -virus, only one report on clinical signs and lesions in rats (MHG-strain) [9], positive serological findings may indicate the presence of a yet uncharacterised virus (?rat cardiovirus?...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1992
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.89.6.2061